Opuntia diploursina is a species in the Cactaceae family, that grows near the Grand Canyon and Lake Mead National Recreation Area. This species is a close relative of Opuntia erinacea but "...differs in minor spines more closely appressed to pad surface, spines smaller in diameter and more flexible, inter-areolar distance less, upright growth habit, larger fruit with longer, more flexible spines, larger seeds, and diploid chromosome number (2n=22)".