Strophanthus kombe, the kombe arrow poison, is a vine that grows in the tropical regions of Eastern Africa, and is part of the genus Strophanthus, which contains approximately 38 species. S. kombe contains a cardiac glycoside which directly affects the heart. Historically, both the seeds and roots of the plant were used in the preparation of poison arrowheads used for hunting. Today, the seeds are used pharmaceutically for patients with certain heart conditions that affect blood circulation. The seeds are traded primarily with Europe, but have also been exported to the United States and Japan.