Penstemon degeneri is a species of flowering plant in the plantain family known by the common name Degener's beardtongue. It is endemic to Colorado in the United States, where it occurs in and around the Arkansas River Canyon in Fremont, Custer, and Chaffee Counties. This species was described in 1965 from a specimen collected by Otto and Isa Degener in Fremont County. There are about 14 occurrences of the plant, which are located in Royal Gorge, the Pike-San Isabel National Forest, and Bureau of Land Management lands. Many aspects of the plant's ecology and conservation are unknown.