Isocoma gypsophila is a Mexican plant species in the sunflower family. It has been found in the States of Zacatecas and Nuevo León. Isocoma gypsophila is a small perennial herb up to 10 cm (4 inches) tall, the stems mostly reclining on the ground and forming a mat. The plant produces one or two flower heads on the tips of branches, each head containing 30-40 disc flowers but no ray flowers.