Grevillea tetrapleura is a shrub of the genus Grevillea native to an area in the Goldfields-Esperance region of Western Australia. The low dense spreading spiny shrub typically grows to a height of 0.1 to 0.9 metres (0.3 to 3.0 ft) and has non-glaucous branchlets. It has simple leaves with a blade that is 15 to 50 millimetres (0.59 to 1.97 in) in length and 1 mm (0.04 in) wide. It blooms between July and September and produces an axillary raceme irregular inflorescence with pink flowers and pink styles. Later it forms ridged or ribbed ellipsoidal glabrous fruit that are 10 to 13 mm (0.4 to 0.5 in) long.