Grevillea shuttleworthiana is a shrub of the genus Grevillea native to an area in the Wheatbelt and Goldfields-Esperance regions of Western Australia. The shrub typically grows to a height of 0.5 to 3 metres (1.6 to 9.8 ft) and has non-glaucous branchlets. It has simple, flat, obovate and undissected leaves with a blade that is 8 to 55 millimetres (0.31 to 2.17 in) long and 5 to 27 mm (0.20 to 1.06 in) wide. It blooms from July to September and produces an axillary or terminal raceme regular inflorescence with yellow flowers and yellow styles. Later it forms smooth or rugose obovoid glabrous fruit that is 7 to 17 mm (0.3 to 0.7 in) long.