Grevillea polybotrya is a shrub of the genus Grevillea native to an area in the Mid West and Wheatbelt regions of Western Australia. The erect, bushy and non lignotuberous shrub typically grows to a height of 1 to 4 metres (3 to 13 ft) and has non-glaucous branchlets. It has simple undissected flat obovate leaves with a blade that is 12 to 50 millimetres (0.5 to 2.0 in) long and 6 to 12 mm (0.24 to 0.47 in) wide. It blooms from September to Decmeber and produces an terminal raceme irregular inflorescence with white, cream or rarely pink flowers and styles. Later it forms ribbed or ridged obovoid or ellipsoidal fruit that is 11 to 15 mm (0.4 to 0.6 in) long.