Hyloxalus patitae is a species of frog in the Dendrobatidae family. It is endemic to Peru where it is only known from its type locality near Comunidad Nativa de Davis, Cordillera El Sira, Pasco Region. It might occur in the El Sira Communal Reserve.Its natural habitats are humid rainforests, especially alongside small streams and near waterfalls. It is potentially threatened by logging in the lower parts of the Cordillera El Sira.