Hyloxalus is a genus of poison dart frogs. The genus is distributed in Central and South America, from Panama south to Peru (along the Pacific coast), along with Venezuela, Colombia and Ecuador. Species also inhabit the eastern foothills of the Andes in Bolivia to Venezuela, east to the upper Amazon Basin. Many Hyloxalus species, such as the cream-back, bear superficial resemblances to hylids, such as the presence of small webs between their toes, and the fact that the discs at the end of their toes are slightly adhesive. This may be one of the oldest of dendrobatid genera; if this is the case, the genus has changed little since it first evolved.