Acropora microphthalma is a species of acroporid coral found in the Red Sea, the Gulf of Aden, the southwest and northern Indian Ocean, the central Indo-Pacific, Australia, Southeast Asia, Japan, the East China Sea and the oceanic west and central Pacific Ocean. It is also found in the Line Islands. It occurs in shallow tropical reefs on upper reef slopes, in turbid water and in sandy lagoons. It can be found from depths of 5–25 m.