Titanoeca quadriguttata is a species of spider in the family Titanoecidae. It is widespread in Europe, though absent from Great Britain, and is found in Austria, Belgium, Bulgaria, Corsica, Croatia, Czech Republic, France, Germany, Greece, Hungary, Italy, Liechtenstein, Moldova, Russia, Slovakia, Spain, Switzerland, the Netherlands, Ukraine. The spiders are mature in spring; adults can be found from May to July in limestone areas of Germany. The male resembles superficially the male of Callilepis schuszteri (Gnaphosidae), but the latter has protruding spinnerets and a silvery carapax.