Cameraria serpentinensis is a moth of the Gracillariidae family. It is known from California, United States. The length of the forewings is 3.2-4.2 mm. The larvae feed on Quercus douglasii, Quercus dumosa, Quercus durata and Quercus × alvordiana. They mine the leaves of their host plant. The mine is ovoid. The epidermis is opaque, brown. All mines cross the midrib and consume 60%-90% of the leaf surface. The mines are solitary and normally with two folds, but rarely one. These folds are not necessarily parallel to each other. The leaf is bowed up with a sunken area at the middle of leaf.