Caloptilia hypericella is a moth of the Gracillariidae family. It is known from Canada (Québec) and the United States (Cincinnati, Ohio, Kentucky, Michigan and West Virginia). The wingspan is about 8 mm. The larvae feed on Hypericum cistifolium, Hypericum punctatum and Hypericum sphaerocarpum. They mine the leaves of their host plant. The mine has the form of a small linear mine on the upperside of the leaf, enlarged into an elongate blotch, which becomes tentiform, resembling a small Phyllonorycter mine.