Ecsenius axelrodi, known commonly as the Axelrod's clown blenny or the Axelrod's combtooth blenny, is a species of ray-finned fish in the family Blenniidae, the combtooth blennies. It is found in shallow water on coral reefs in the western central Pacific Ocean. It was first described by Victor Gruschka Springer in 1988 and named in honour of the American ichthyologist Herbert Richard Axelrod.