Saccharomyces boulardii is a tropical species of yeast first isolated from lychee and mangosteen fruit in 1923 by French scientist Henri Boulard. Saccharomyces boulardii (synonym: Saccharomyces cervisiae var boulardii and saccharomyces cerevisiae Hansen CBS 5926) is a yeast that could be assigned to the subtype of saccharomyces cerevisiae species. It is related to, but distinct from, Saccharomyces cerevisiae in several taxonomic, metabolic, and genetic properties. S. boulardii is sometimes used as a probiotic with the purpose of introducing beneficial active cultures into the large and small intestine, as well as conferring protection against pathogenic microorganisms in the host. However, in immunocompromised individuals, S. boulardii has been associated with fungemia or localized infecti