The Prince Charles stream tree frog, Hyloscirtus princecharlesi, is a species of frog in the Hylidae family found in Ecuador. It is considered an endangered species threatened by habitat loss, climate change, pathogens, and other hazards. In June 2012, the species was described as new to science by Luis A. Coloma et al. in the journal Zootaxa and named in honour of Prince Charles, recognising the Prince's work advocating rainforest conservation.