Ectoedemia empetrifolii is a moth of the Nepticulidae family. It is found in Greece (Peloponnesus). The larvae feed on Hypericum empetrifolium. They mine the leaves of their host plant. The mine consists of a narrow corridor, generally along the leaf margin, widening into a blotch that occupies almost the complete leaf. The frass is concentrated in the basal part of the blotch.