Grevillea patentiloba is a shrub of the genus Grevillea native to an area in the Great Southern, Wheatbelt and Goldfields-Esperance regions of Western Australia. The spreading, straggling shrub typically grows to a height of 0.3 to 3 metres (1 to 10 ft) and has non-glaucous branchlets. It has simple dissected leaves with a blade that is 30 to 45 millimetres (1.2 to 1.8 in) long. It blooms from June to October and produces an terminal raceme irregular inflorescence with red or pink flowers. Later it forms ribbed or ridged obovoid or ellipsoidal glabrous fruit that is 10 to 14 mm (0.4 to 0.6 in) long.