Psilocybe neoxalapensis is a species of psilocybin mushroom in the family Strophariaceae. Found in Veracruz, Mexico, it was originally described in 2005 under the name Psilocybe novoxalapensis, but this naming was later determined to be invalid, and it was renamed P. neoxalapensis in 2009. It is in the Psilocybe fagicola complex with Psilocybe fagicola, Psilocybe oaxacana, Psilocybe banderillensis, Psilocybe columbiana, Psilocybe keralensis, Psilocybe herrerae, and Psilocybe teofiloi.