Pergularia is a genus of the botanical family Apocynaceae. Pergularia daemia is a perennial twinning herb that grows along the roadsides of India and tropical and subtropical regions in South Asia, Africa, and Australia. Pharmacological activities include antiinflammatory, hepatoprotective, anticancer, antidiabetic, antioxidant, antibacterial, antifungal, analgesic, anti-infertility and central nervous system depressant activity. moved to other genera (Cionura, Marsdenia, Metaplexis, Strophanthus, Telosma, Tylophora, Vallaris )