Lysapsus limellum, sometimes known as the Uruguay harlequin frog, is a species of frog in the Hylidae family found in northern Argentina, Bolivia, Brazil, Paraguay, and Uruguay. Its natural habitats are moist savanna, subtropical or tropical seasonally wet or flooded lowland grassland, rivers, swamps, freshwater lakes, freshwater marshes, and pastureland. It is locally impacted by habitat loss.