The grapeleaf skeletonizer (Harrisina americana) is a moth in the family Zygaenidae. It is widespread in the eastern half of the United States, and commonly noticed defoliating grapes, especially of the Virginia creeper (Parthenocissus quinquefolia). The western grapeleaf skeletonizer (Harrisina metallica) is very similar to and slightly larger than H. americana, but their distributions are different. Members of this family all produce HCN (hydrogen cyanide) a potent antipredator toxin.