Xylophanes titana is a moth of the family Sphingidae. It is known from Mexico, Belize, Guatemala, Honduras, Nicaragua, Costa Rica, Panama, Colombia, Ecuador, Peru, Bolivia, Paraguay, Argentina, Venezuela, French Guiana, Brazil and probably Guyana and Suriname. There are probably at least two generations per year. In Costa Rica, adults have been recorded in every month except March. In Brazil, adults have been recorded in December. The larvae feed on Rubiaceae species and have been recorded on Manettia reclinata in Costa Rica.