Hyles annei is a moth of the family Sphingidae. It is known from Chile, Bolivia, western Peru and Argentina. Adults are on wing in January, August and probably other months. The larval hosts are unknown, but they will probably feed on a wide range of plants including Epilobium, Mirabilis, Oenothera, Vitis, Lycopersicon, Portulaca, Fuchsia, Gaura lindheimerii, Alternanthera pungens and Euphorbia dentata or related plants found in a dry climate.