Manduca hannibal is a moth of the family Sphingidae. It is found from Mexico, Belize, Nicaragua and Costa Rica to Surinam, Venezuela, Ecuador, Brazil, Bolivia and north-eastern Argentina. The wingspan is 99–114 mm. There is a whitish subbasal band on the hindwing upperside and a generally rather large dirty white patch within the black central band near the anal angle. There are multiple generations per year in Costa Rica, with adults recorded year round except January and March. In Bolivia, adults have been recorded in February, April, August, October and December.