Coptotriche zelleriella is a moth of the family Tischeriidae. It was described by Clemens in 1859. It is found in Ontario, Quebec, Arkansas, the District of Columbia, Florida, Illinois, Kentucky, Massachusetts, Missouri, New Jersey, New York, North Carolina, Ohio, Pennsylvania, Texas, Virginia and West Virginia. The larvae feed on Quercus alba, Quercus bicolor, Quercus montana, Quercus prinus, Quercus rubra and Quercus stellata. They mine the leaves of their host plant.