Agonopterix issikii is a moth in the Depressariidae family. It was described by Clarke in 1962. It is found in Japan. The wingspan is 18–19 mm. The forewings are brown, suffused with fuscous. The extreme base is pale brownish-buff, this area containing a short black transverse bar, bordered by a black spot. There is fuscous suffusion in the pale basal area. There are also three black spots in the cell, the outer two forming a fuscous blotch. Between this blotch and the apex there are three fuscous spots and a broken fuscous line around the termen. The hindwings are bronzy-grey darkening to fuscous apically.