Agonopterix glyphidopa is a moth in the Depressariidae family. It was described by Meyrick in 1828. It is found in South Africa. The wingspan is about 17 mm. The forewings are pale ochreous, with a narrowly black base. The costal area is tinged with crimson anteriorly and there is an oblong dark fuscous patch occupying the dorsal two-thirds of the wing from near the base to two-third, followed posteriorly and above beyond the middle by some fuscous suffusion and dark fuscous irroration. The hindwings are light grey.