Dichomeris thrypsandra is a moth in the Gelechiidae family. It was described by Meyrick in 1923. It is found in Ecuador. The wingspan is 14-15 mm. The forewings are dark grey, slightly speckled yellow-whitish and with a narrow light yellowish subcostal streak from the base, becoming obsolete at about four-fifth. There are slightly oblique pale yellowish lines from the dorsum before the middle and towards the tornus, terminating in the subcostal streak, edged posteriorly by blackish suffusion. There is an indistinct transverse mark of blackish and yellow-whitish scales on the end of the cell. The hindwings of the males are yellow-whitish, with long hair-scales on each side of the submedian fold, the apex suffused light grey. The female hindwings are light grey.