The Miller Lake lamprey (Entosphenus minimus) is a species of lamprey in the Petromyzontidae family. It is endemic to the United States. Its natural habitat is the Miller Lake drainage. This species is of special interest for two reasons: 1) it has an extremely limited distribution, with all known animals contained within a single small drainage system, and 2) it is the smallest known parasitic lamprey in the world. The Miller lake lamprey was presumed extinct in 1958, after state fishery managers attempted to eradicate the lamprey from the lake because it was feeding on the introduced trout. The known larval streams for this lamprey were treated with lampricide and a barrier was erected to prevent adults from entering to spawn.