Makapania is an extinct genus of large caprid or ovibovine from the Pliocene and Pleistocene of southern and East Africa. It is remarkable in that its horns were positioned laterally. Its closest living relatives are the musk-ox of North America and the takin of Tibet. Its body weight is estimated to have been about 263 kg. Makapania is thought to have been both a browser and a grazer. It probably preferred grasses, and would have required a nearby source of permanent water.