Kelyophis (/keɪliːˈoʊfɪs/; meaning 'small serpent' from the Malagasy word kely (meaning "small") and the Greek word ὄφις (ophis, meaning "serpent")) is an extinct genus of nigerophiid snake which existed in Madagascar during the Late Cretaceous. The type species is Kelyophis hechti. Trunk vertebrae have been found from the Maastrichtian-age Maevarano Formation in the Mahajanga Basin. Kelyophis is similar to other nigerophiids in its small size, long centra with posterior surfaces that deflect slightly downward, tubercular-shaped neural spines that are directed toward the back of the neural arches, and several other features of the vertebrae.