Mesosuchus is an extinct genus of basal rhynchosaur from early Middle Triassic (early Anisian stage) deposits of Eastern Cape, South Africa. It is known from the holotype SAM 5882, a partial skeleton, and from the paratypes SAM 6046, SAM 6536, SAM 7416 and SAM 7701 from the Aliwal North Euparkeria site. It was found in the middle deposits of the Burgersdorp Formation of the Beaufort Group (Karoo Basin) and referred to Subzone B of the Cynognathus Assemblage Zone. It was first named by David Meredith Seares Watson in 1912 and the type species is Mesosuchus browni.