Orophodontidae is a family of extinct ground sloths within the order Pilosa and suborder Folivora. The taxon is often disused with genus members reassigned. This family is related to the other families of extinct ground sloths, Megatheriidae, Mylodontidae, Nothrotheriidae, and Scelidotheriidae. The only extant families of the suborder Folivora are Bradypodidae and Megalonychidae. †Orophodontidae members prior to reassignment.