Homotherium is an extinct genus of machairodontine saber-toothed cats, often termed scimitar-toothed cats, that ranged from North America, South America, Eurasia, and Africa during the Pliocene and Pleistocene epochs (5 mya – 28,000 years ago), existing for approximately 5 million years. It first became extinct in Africa some 1.5 million years ago. In Eurasia it survived until about 30,000 years ago. In South America it is only known from a few remains in the northern region (Venezuela), from the mid-Pleistocene. The most recent remains of Homotherium dates to 28,000 years BP.