Xyronomys is an extinct genus of small mammals from the Paleocene of North America, with two described species. The genus lies within the extinct order Multituberculata within the suborder Cimolodonta and family Neoplagiaulacidae. A second species Xyronomys robinsoni was found in Puercan (Lower Paleocene)-age strata of Colorado, USA and was named by Middleton and Dewar in 2004. Material assigned to this genus has also been reported from Rav W-1 in Saskatchewan, Canada.