Amphimachairodus is an extinct genus of large machairodonts belonging to the clade known as Eumachairodontia (true saberteeth) along with relatives like Smilodon and Homotherium. It is also a member of the tribe Homotherini within Machairodontidae and is most closely related to such species as Xenosmilus, Homotherium itself, and Nimravides. It inhabited Eurasia, Northern Africa and North America during the late Miocene epoch.