Zygolophodon is an extinct genus of African, Asian, North American and European mammutid that lived from the Miocene to the Middle Pleistocene. It may have evolved from Tetralophodon. While collecting fossils in the Clarno Formation of Oregon during 1941, noted paleobotanists Alonzo W. Hancock and Chester A. Arnold recovered the most complete Zygolophodon skull known at the time.