Acanthomeridion is an extinct arthropod found in the Chengjiang fauna deposits of China. In 1997, it was placed in its own, monotypic family, Acanthomeridiidae. It is known from eight specimens, all found in China. Acanthomeridion was a 35 mm-long animal, with 11 segments ending in rear-facing spines. The head features free cheeks separated by the rest of the head by sutures. This is analogous with trilobites. Otherwise, affinities are unclear.