Ophiotrichidae are a family of ophiurid brittle stars within the infraorder Gnathophiurina. All have arms with delicate translucent, thorny spines. The arms are flexible in all directions. The jaws contain clusters of well-developed tooth papillae on the apex but not on the sides. There are no mouth papillae. Inside the mouth edge there is a second pair of tube feet. They show large radial shields. The dorsal surface of the disc is covered with spines and thorny towers.