Acanthamoebidae is a family of single celled eukaryotes within the group Amoebozoa. It gets its name from Acanthamoeba, its best known member. However, it also includes other species, such as Comandonia operculata and Protacanthamoeba bohemica. Many kinds of Acanthamoebidae are highly prevalent in the soil and water of a variety of environments. They are similar to Hartmannella, but have differently structured pseudopodia, in regard to the actin microfilaments that comprise them. Its most prominent member, Acanthamoeba, can be potentially pathogenic to humans and animals.