The Didymosphaeriaceae are a family of fungi in the order Pleosporales. Taxa have a cosmopolitan distribution, and are saprobic in both woody and herbaceous plants. Some species are parasitic on other fungi. The validity of the family as a distinct taxonomic unit has been questioned in a recent (2014) publication that suggests that the genera Appendispora, Phaeodothis, Roussoella, and Verruculina should be moved into other families.