Phyllodactylus lepidopygus is a gecko belonging to the genus Phyllodactylus ("leaf-toed" geckos). It was described by Tschudi in 1845. The species' natural habitat is restricted to the central coast of Peru, between the regions of Ica and Ancash. In the Lima region, a large portion of its coastal habitat has been negatively affected by urban development. Within the city of Lima, sightings were reported in 2004 in the Pantanos de Villa Reserved Zone, where the species may have found a good opportunity to survive. Large populations of this species are found in the lomas (fog-supported vegetation communities) of Pachacamac and Lachay.