Zophodia leithella is a species of snout moth in the genus Zophodia. It was described by Dyar in 1928. It is found in northern Venezuela and Colombia, in the Caribbean (Curaçao) and in southern Mexico. The wingspan is 30–33 mm. The forewings are greyish brown with darker markings and the hindwings are almost wholly white in males and mainly fuscous in females.